We utilize molecular and cell biology, biochemistry, electrophysiology, and mouse genetics to understand the regulation of excitability homeostasis and how the dysregulation of that affects behavior.
Check out our latest work 👇 Lee et al., 2023 Tumor suppressor p53 modulates activity-dependent synapse strengthening, autism-like behavior and hippocampus-dependent learning (in press) Lizarazo et al., 2022 Amyloid beta induces Fmr1-dependent translational suppression and hyposynchrony of neural activity via phosphorylation of eIF2α and eEF2 Lee et al., 2021 Infantile spasms-linked Nedd4-2 mediates hippocampal plasticity and learning via cofilin signaling
