We utilize molecular and cell biology, biochemistry, electrophysiology, and mouse genetics to understand the regulation of excitability homeostasis and how the dysregulation of that affects behavior.
Check out our latest work 👇 Kumar et al., 2024 mGluR7 allosteric modulator AMN082 corrects protein synthesis and pathological phenotypes in FXS Yook et al., 2024 Hyperfunction of PSD-95 Promotes Seizure Response in Early-Stage Aβ Pathology Lee et al., 2023 Tumor suppressor p53 modulates activity-dependent synapse strengthening, autism-like behavior and hippocampus-dependent learning